Rules FAQ
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Joseran triggers during Step 1.3 in the plot phase, after the first player is chosen, but before resolving any When Revealed abilities. 
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You can trigger the reaction if you become the first player with Seize the Initiative. 
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You "become" the first player again even if you were the first player the previous round as well. 
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Cards under a player's agenda are not considered to be in play. They are essentially removed from the game permanently, unless that player is playing The Conclave or Archmaester Marwyn. A player can always look at any facedown card under their agenda. 
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A player who is not playing an agenda cannot place cards under it. Joseran can still be triggered though, as long as at least one player is playing an agenda. 
